A role for nitrergic system in the antidepressant-like effects of chronic lithium treatment in the mouse forced swimming test

@article{Ghasemi2009ARF,
  title={A role for nitrergic system in the antidepressant-like effects of chronic lithium treatment in the mouse forced swimming test},
  author={Mehdi Ghasemi and Hamed Sadeghipour and Gholamreza Poorheidari and Ahmad Reza Dehpour},
  journal={Behavioural Brain Research},
  year={2009},
  volume={200},
  pages={76-82}
}
NMDA receptor/nitrergic system blockage augments antidepressant-like effects of paroxetine in the mouse forced swimming test
TLDR
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On the effect of minocycline on the depressive-like behavior of mice repeatedly exposed to malathion: interaction between nitric oxide and cholinergic system
TLDR
The investigation indicates the essential role for NO/cGMP pathway in malathion-induced depressive-like behavior and antidepressant-like effect of minocycline and the interaction between nitrergic and cholinergic systems are suggested to be involved in malathon-induced depression.
Agmatine enhances the antidepressant-like effect of lithium in mouse forced swimming test through NMDA pathway.
The effects of the lithium salt of GABA on the subcellular metabolic profile of L-arginine in the prefrontal cortex and striatum of rats during chronic stress
TLDR
Although this treatment did not influence the stress-induced shifts in the activity of cNOS, it prevented stimulation of the iNOS/NO system of mitochondria due to blockage of NO hyperproduction and nitrosative stress, whose development results in the disturbance of energetic processes in these brain areas.
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References

SHOWING 1-10 OF 68 REFERENCES
Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice
TLDR
The results indicate that either the synthesis of NO or the inhibition of its synthesis may produce antidepressantlike effects when assessed in the FST and TST, which could indicate that NO has a dual role in the modulation of depression.
Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats
TLDR
The findings suggest that NO might be an important modulator of depression in rats, as well as a test for screening new antidepressant agents.
The effects of combined treatment with MK-801 and antidepressant drugs in the forced swimming test in rats.
TLDR
The obtained results indicate that mainly a dopamine mechanism seems to be involved in the synergistic action of MK-801 and the antidepressants in the forced swimming test.
Additive effects of lithium and antidepressants in the forced swimming test: further evidence for involvement of the serotoninergic system
TLDR
The hypothesis that the potentiation by lithium of ADS is via direct 5HT mechanisms, indirect via a NA/5HT link, and/or by second messenger systems is supported.
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