• DOI:10.1007/s00213-011-2362-9
Corpus ID: 9255941

A role for neuropeptide Y Y5 but not the Y1-receptor subtype in food deprivation-induced reinstatement of heroin seeking in the rat

@article{Maric2011ARF,
  title={A role for neuropeptide Y Y5 but not the Y1-receptor subtype in food deprivation-induced reinstatement of heroin seeking in the rat},
  author={Tia Maric and F. Sedki and D. Chafetz and Nick Schoela and U. Shalev},
  journal={Psychopharmacology},
  year={2011},
  volume={218},
  pages={693-701}
}

• Tia Maric, F. Sedki, +2 authors U. Shalev
• Published 2011
• Psychology, Medicine
• Psychopharmacology

Rational and objectivesNeuropeptide Y (NPY), an orexigenic peptide that is released during periods of food restriction, has been shown to have a significant modulatory impact on drug-related behaviors. We have previously reported that both acute food deprivation (FD) and NPY injections can reinstate extinguished drug-seeking behavior, a proposed animal model of relapse to drug abuse. However, it is not clear whether the FD effect on drug seeking is dependent on NPY transmission. Here, we used… Expand

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