A role for nerve growth factor in sympathetic sprouting in rat dorsal root ganglia.

@article{Jones1999ARF,
  title={A role for nerve growth factor in sympathetic sprouting in rat dorsal root ganglia.},
  author={Mark M. Jones and J. B. Munson and Stephen W.N. Thompson},
  journal={Pain},
  year={1999},
  volume={79 1},
  pages={21-9}
}
The role of nerve growth factor (NGF) and glial-derived neurotrophic factor (GDNF) in sympathetic sprouting within the dorsal root ganglion was investigated. In nerve-intact rats, intrathecal NGF (1 mg/ml, 14 days) but not GDNF (1 mg/ml, 14 days) induced extensive sprouting of tyrosine hydroxylase immunoreactive (TH-IR) fibres and formation of pericellular… CONTINUE READING