A role for nerve growth factor in collateral reinnervation from sensory nerves in the guinea pig.

@article{Owen1989ARF,
  title={A role for nerve growth factor in collateral reinnervation from sensory nerves in the guinea pig.},
  author={David R. Owen and Ann Logan and Peter P. Robinson},
  journal={Brain research},
  year={1989},
  volume={476 2},
  pages={248-55}
}
We have investigated whether chronic nerve growth factor (NGF) depletion affects the development of a transmedian collateral reinnervation. The extent of transmedian innervation of the skin supplied by the left inferior alveolar nerve (IAN) was determined either immediately, 2 days or 7-9 weeks after sectioning and preventing regeneration of the contralateral IAN and in another group of animals left to recover for 7-9 weeks but also autoimmunised against NGF. Transmedian innervation was… CONTINUE READING