A role for microtubule dynamics in phagosome movement.

@article{Blocker1998ARF,
  title={A role for microtubule dynamics in phagosome movement.},
  author={Ariel Blocker and Gareth Griffiths and J C Olivo and Anthony A. Hyman and Fedor F. Severin},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 3)},
  pages={303-12}
}
We have shown previously that intracellular phagosome movement requires microtubules. Here we provide evidence that within cells phagosomes display two different kinds of microtubule-based movements in approximately equal proportions. The first type occurs predominantly in the cell periphery, often shortly after the phagosome is formed, and at speeds below 0.1 microm/second. The second is faster (0.2-1.5 micron/second) and occurs mainly after phagosomes have reached the cell interior. Treating… CONTINUE READING

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