A role for lipid rafts in immune cell signaling.

  title={A role for lipid rafts in immune cell signaling.},
  author={Yohko U. Katagiri and Nobutaka Kiyokawa and Jiro Fujimoto},
  journal={Microbiology and immunology},
  volume={45 1},
Cross-linking of surface receptors in hematopoietic cells results in the enrichment of these receptors in the rafts along with other downstream signaling molecules. A possible explanation how signal is transduced through the plasma membrane has arisen from the concept of raft. From the study of cellular responses in the plasma membrane which enrich members of the Src-family tyrosine kinase, rafts can function as centers of signal transduction by forming patches. Under physiological conditions… CONTINUE READING