A role for lateral hypothalamic orexin neurons in reward seeking

@article{Harris2005ARF,
  title={A role for lateral hypothalamic orexin neurons in reward seeking},
  author={Glenda C. Harris and Mathieu E Wimmer and Gary Aston-Jones},
  journal={Nature},
  year={2005},
  volume={437},
  pages={556-559}
}
Food and drug cravingThe activation of neurons in the lateral hypothalamus of the brain that contain the novel neuropeptide orexin may be responsible for the cravings experienced by both overeaters and drug addicts. A study in rats shows that these orexin neurons are strongly stimulated in proportion to the degree of food- or drug-seeking that animals exhibit in a conditioning experiment. Direct stimulation of these orexin neurons causes a relapse of drug-seeking behaviour, and a similar… CONTINUE READING
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