A role for free radicals and nitric oxide in delayed recovery in aged rats with chronic constriction nerve injury.

Abstract

Using a reversible chronic constriction injury (CCI) model of neuropathic pain, we previously demonstrated that changes in thermal hyperalgesia correlate with the changes in peripheral microvascular blood flow in the affected paw, and that recovery can be assessed by normalization of both behavioral and vascular responses. Using the same model, this study… (More)

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