A role for central glucagon-like peptide-1 in temperature regulation.

  title={A role for central glucagon-like peptide-1 in temperature regulation.},
  author={Donal O'Shea and Irene Gunn and Xianming Chen and Stephen R. Bloom and J R Herbert},
  volume={7 3},
We have already established that central glucagon-like peptide-1 (GLP-1) has a role in the central control of food intake. In this study, experiments were conducted to establish the effect of acute intraperitoneal (i.p.) and intracerebroventricular (i.c.v.) administration of GLP-1 on temperature. Injection of 10 micrograms GLP-1 i.c.v. caused a significant reduction in temperature over the subsequent 2 h and reduced food intake as expected. Both effects were blocked by prior i.c.v… CONTINUE READING

From This Paper

Topics from this paper.
15 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…