A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine

  title={A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine},
  author={Camron D. Bryant and Melissa E. Graham and Margaret G. Distler and Michaelanne B. Munoz and Dongdong Li and Paul Vezina and Greta Sokoloff and Abraham A Palmer},
We previously colocalized a quantitative trait locus (QTL) for sensitivity to the locomotor stimulant effects of methamphetamine (MA) with a QTL for expression of casein kinase 1 epsilon (Csnk1-ɛ) in the nucleus accumbens (NAc). Subsequently, we identified a single nucleotide polymorphism in CSNK1E (rs135745) that was associated with increased sensitivity to the subjective effects of d-amphetamine in healthy human subjects. Based on these results, we hypothesized that differential expression of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 22 extracted citations


Publications referenced by this paper.
Showing 1-10 of 46 references

An inhibitor of casein kinase I epsilon induces phase delays in circadian rhythms under free-running and entrained conditions.

The Journal of pharmacology and experimental therapeutics • 2007
View 7 Excerpts
Highly Influenced

Post-translational modifications regulate the ticking of the circadian clock

Nature Reviews Molecular Cell Biology • 2007
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…