A role for angiotensin-converting enzyme in the characterization, enrichment, and proliferation potential of adult murine pituitary colony-forming cells.

@article{Lepore2006ARF,
  title={A role for angiotensin-converting enzyme in the characterization, enrichment, and proliferation potential of adult murine pituitary colony-forming cells.},
  author={Diana A Lepore and V. Jokubaitis and Paul J. Simmons and Kelly N. Roeszler and Ralph Rossi and Karl -Heinz Bauer and Paul Quinton Thomas},
  journal={Stem cells},
  year={2006},
  volume={24 11},
  pages={2382-90}
}
Recently, we described a rare cell type within the adult murine pituitary gland with progenitor cell hallmarks (PCFCs). PCFCs are contained exclusively within a subpopulation of cells that import fluorescent beta-Ala-Lys-Nepsilon-AMCA (7-amino-4-methylcoumarin-3-acetic acid). Herein, we investigate the utility of cell surface molecules angiotensin-converting enzyme (ACE) and stem cell antigen-1 (Sca-1) to further enrich for PCFCs. ACE and Sca-1 were expressed on 61% and 55% of AMCA(+)CD45… CONTINUE READING

Similar Papers

Loading similar papers…