A role for adenosine in coronary vasoregulation in man. Effects of theophylline and enprofylline.

  title={A role for adenosine in coronary vasoregulation in man. Effects of theophylline and enprofylline.},
  author={A. Edlund and T. Conradsson and A. Sollevi},
  journal={Clinical physiology},
  volume={15 6},
  • A. Edlund, T. Conradsson, A. Sollevi
  • Published 1995
  • Medicine
  • Clinical physiology
  • Adenosine has been suggested to have a role in regulation of the tone of the cardiac resistance vessels. To elucidate the coronary vasoregulatory role of endogenous adenosine in man, we studied the effects of adenosine receptor antagonism by theophylline on coronary blood flow at rest and during light exercise. However, theophylline may also exert pharmacological effects not related to adenosine antagonism. To clarify the contribution of endogenous adenosine in coronary hyperaemia, the effect… CONTINUE READING
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