A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes.

Abstract

TFIIH is a multifunctional RNA polymerase II transcription factor that possesses DNA-dependent ATPase, DNA helicase, and protein kinase activities. Previous studies have established that TFIIH enters the preinitiation complex and fulfills a critical role in initiation by catalyzing ATP-dependent formation of the open complex prior to synthesis of the first… (More)

Topics

4 Figures and Tables

Slides referencing similar topics