A role for RAD54B in homologous recombination in human cells.

@article{Miyagawa2002ARF,
  title={A role for RAD54B in homologous recombination in human cells.},
  author={Kiyoshi Miyagawa and Takanori Tsuruga and Aiko Kinomura and Kiyomi Usui and Mari Katsura and Satoshi Tashiro and Hiromu Mishima and Kozo Tanaka},
  journal={The EMBO journal},
  year={2002},
  volume={21 1-2},
  pages={
          175-80
        }
}
In human somatic cells, homologous recombination is a rare event. To facilitate the targeted modification of the genome for research and gene therapy applications, efforts should be directed toward understanding the molecular mechanisms of homologous recombination in human cells. Although human genes homologous to members of the RAD52 epistasis group in yeast have been identified, no genes have been demonstrated to play a role in homologous recombination in human cells. Here, we report that… CONTINUE READING

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