A role for IL-22 in the relationship between intestinal helminths, gut microbiota and mucosal immunity.

@article{Leung2013ARF,
  title={A role for IL-22 in the relationship between intestinal helminths, gut microbiota and mucosal immunity.},
  author={Jacqueline M Leung and P'ng Loke},
  journal={International journal for parasitology},
  year={2013},
  volume={43 3-4},
  pages={253-7}
}
The intestinal tract is home to nematodes as well as commensal bacteria (microbiota), which have coevolved with the mammalian host. The mucosal immune system must balance between an appropriate response to dangerous pathogens and an inappropriate response to commensal microbiota that may breach the epithelial barrier, in order to maintain intestinal homeostasis. IL-22 has been shown to play a critical role in maintaining barrier homeostasis against intestinal pathogens and commensal bacteria… CONTINUE READING

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Philosophical transactions of the Royal Society of London. Series B, Biological sciences • 2015

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