A role for H2B ubiquitylation in DNA replication.

@article{Trujillo2012ARF,
  title={A role for H2B ubiquitylation in DNA replication.},
  author={Kelly M. Trujillo and Mary Ann Osley},
  journal={Molecular cell},
  year={2012},
  volume={48 5},
  pages={734-46}
}
The monoubiquitylation of histone H2B plays an important role in gene expression by contributing to the regulation of transcription elongation and mRNA processing and export. We explored additional cellular functions of this histone modification by investigating its localization to intergenic regions. H2B ubiquitylation is present in chromatin around… CONTINUE READING