A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies

@article{Jao2017ARF,
  title={A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies},
  author={Li-En Jao and Abdalla Akef and S. R. Wente},
  journal={Molecular Biology of the Cell},
  year={2017},
  volume={28},
  pages={120 - 127}
}
A DEAD-box helicase regulator has a novel role in centrosome and cilia function, ensuring proper pericentrin recruitment, microtubule organization, and ciliary beating. Independent of mRNA export function, Gle1 forms a toroid structure around the mother centriole. This affects human development and disease mechanisms. 
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