A role for DNA polymerase θ in the timing of DNA replication.

Abstract

Although DNA polymerase θ (Pol θ) is known to carry out translesion synthesis and has been implicated in DNA repair, its physiological function under normal growth conditions remains unclear. Here we present evidence that Pol θ plays a role in determining the timing of replication in human cells. We find that Pol θ binds to chromatin during early G1… (More)
DOI: 10.1038/ncomms5285

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@article{FernandezVidal2014ARF, title={A role for DNA polymerase θ in the timing of DNA replication.}, author={Anne Fernandez-Vidal and Laure Guitton-Sert and Jean-Charles Cadoret and Marjorie Drac and Etienne Schwob and Giuseppe Baldacci and Christophe Cazaux and Jean-Sebastien Hoffmann}, journal={Nature communications}, year={2014}, volume={5}, pages={4285} }