A role for DNA methylation in gastrulation and somite patterning.

  title={A role for DNA methylation in gastrulation and somite patterning.},
  author={C. Cristofre Martin and Lynda Laforest and M A Akimenko and Marc Ekker},
  journal={Developmental biology},
  volume={206 2},
DNA methylation constitutes an important epigenetic factor in the control of genetic information. In this study, we analyzed expression of the DNA methyltransferase gene and examined DNA methylation patterns during early development of the zebrafish. Maternal transcripts of the zebrafish DNA methyltransferase gene (MTase) are ubiquitously present at high levels in early embryos with overall levels decreasing after the blastula stage. At 24 h, methyltransferase mRNA is predominantly found in the… CONTINUE READING
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The Zebrafish Book.

  • M. Westerfield
  • 1995
Highly Influential
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