A robustness-based approach to systems-oriented drug design

@article{Kitano2007ARA,
  title={A robustness-based approach to systems-oriented drug design},
  author={Hiroaki Kitano},
  journal={Nature Reviews Drug Discovery},
  year={2007},
  volume={6},
  pages={202-210}
}
Many potential drugs that specifically target a particular protein considered to underlie a given disease have been found to be less effective than hoped, or to cause significant side effects. The intrinsic robustness of living systems against various perturbations is a key factor that prevents such compounds from being successful. By studying complex… CONTINUE READING

2 Figures & Tables

Topic