A robust protein host for anchoring chelating ligands and organocatalysts.

Abstract

In order to put the previously proposed concept of directed evolution of hybrid catalysts (proteins that harbor synthetic transition-metal catalysts or organocatalysts) into practice, several prerequisites must be met. The availability of a robust host protein that can be expressed in sufficiently large amounts, and that can be purified in a simple manner… (More)
DOI: 10.1002/cbic.200700413

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