A roadmap to directed enzyme evolution and screening systems for biotechnological applications.

  title={A roadmap to directed enzyme evolution and screening systems for biotechnological applications.},
  author={R. Mart{\'i}nez and U. Schwaneberg},
  journal={Biological research},
  volume={46 4},
  • R. Martínez, U. Schwaneberg
  • Published 2013
  • Computer Science, Medicine
  • Biological research
  • Enzymes have been long used in man-made biochemical processes, from brewing and fermentation to current industrial production of fine chemicals. The ever-growing demand for enzymes in increasingly specific applications requires tailoring naturally occurring enzymes to the non-natural conditions found in industrial processes. Relationships between enzyme sequence, structure and activity are far from understood, thus hindering the capacity to design tailored biocatalysts. In the field of protein… CONTINUE READING
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