A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer.

@article{Jacobs1990ARO,
  title={A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer.},
  author={Ian J. Jacobs and David H Oram and Janet Fairbanks and Janette Turner and Christopher Frost and Jurgis Gedis Grudzinskas},
  journal={British journal of obstetrics and gynaecology},
  year={1990},
  volume={97 10},
  pages={922-9}
}
Age, ultrasound score, menopausal status, a clinical impression score and serum CA 125 level were assessed to see how they could best distinguish between patients with benign (n = 101) and malignant (n = 42) pelvic masses. Each criteria used alone provided statistically significant discrimination. The most useful individual criteria were a serum CA 125 level of 30 U/ml (sensitivity 81%, specificity 75%) and an ultrasound score of 2 (sensitivity 71%, specificity 83%). Three criteria could be… CONTINUE READING
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