A risk-benefit assessment of topical percutaneous local anaesthetics in children.

@article{Russell1997ARA,
  title={A risk-benefit assessment of topical percutaneous local anaesthetics in children.},
  author={Sunny Russell and Eleanor Doyle},
  journal={Drug safety},
  year={1997},
  volume={16 4},
  pages={279-87}
}
Since its introduction, eutectic lidocaine-prilocaine cream ('EMLA')1 has been found to be an effective topical anaesthetic agent, with a high degree of efficacy, particularly for venepuncture and venous cannulation, and an impressive tolerability profile. Reports of adverse effects are remarkable for their rarity. The only problems that are likely to be encountered are oral ingestion of the cream (which may lead to anaesthesia of the oropharynx and possible toxicity secondary to rapid… CONTINUE READING