A risk-benefit assessment of naltrexone in the treatment of alcohol dependence.

@article{Berg1996ARA,
  title={A risk-benefit assessment of naltrexone in the treatment of alcohol dependence.},
  author={Barbara J. van den Berg and Helen M. Pettinati and Joseph R. Volpicelli},
  journal={Drug safety},
  year={1996},
  volume={15 4},
  pages={
          274-82
        }
}
There is a great deal of interest in the use of naltrexone as a treatment for alcohol (ethanol) dependence since there is a rapidly expanding body of evidence to support its efficacy and tolerability in this indication. Naltrexone, a long-acting, nonselective opioid receptor antagonist has been shown to reduce alcohol intake when combined with behavioural treatment. Naltrexone may prevent the return to clinically significant drinking by blocking the pleasurable effects or "high' associated with… CONTINUE READING

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