A rhesus macaque model of Asian-lineage Zika virus infection

@inproceedings{Dudley2016ARM,
  title={A rhesus macaque model of Asian-lineage Zika virus infection},
  author={Dawn M. Dudley and Matthew T Aliota and Emma L Mohr and Andrea M. Weiler and Gabrielle Lehrer-Brey and Kim L. Weisgrau and Mariel S Mohns and Meghan E. Breitbach and Mustafa N Rasheed and Christina M Newman and Dane D. Gellerup and Louise H. Moncla and Jennifer L. Post and Nancy J Schultz-Darken and Michele L. Schotzko and Jennifer Marie Hayes and Josh A Eudailey and M Anthony Moody and Sallie R. Permar and Shelby L O'Connor and Eva G Rakasz and Heather A. Simmons and Saverio Capuano and Thaddeus G Golos and Jorge E Osorio and Thomas C Friedrich and David H. O'Connor},
  booktitle={Nature communications},
  year={2016}
}
Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain-Barré syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. Animal models of infection are thus urgently needed. Here we show that rhesus macaques are susceptible to infection by an Asian-lineage ZIKV closely related to strains currently circulating in the Americas. Following subcutaneous inoculation, ZIKV RNA is detected in plasma 1 day post infection (d.p.i.) in all animals (N… CONTINUE READING
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