A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration.

@article{Madsen1998ARE,
  title={A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration.},
  author={Flemming Madsen and K Eberth and John D. Smart},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={1998},
  volume={50 1-3},
  pages={167-78}
}
The ability of mucoadhesive polymers to produce a large increase in the resistance to deformation when incorporated into a mucus gel, relative to when the mucus gel and test materials are evaluated separately at the same concentrations, has been reported in several previous studies. It has been proposed that this phenomenon, termed rheological synergism, can be used as a measure of the strength of the mucoadhesive interaction. In this investigation rheological synergism was investigated for a… CONTINUE READING

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