A revised model of ex-vivo reduction of hexavalent chromium in human and rodent gastric juices.


Chronic oral exposure to hexavalent chromium (Cr-VI) in drinking water has been shown to induce tumors in the mouse gastrointestinal (GI) tract and rat oral cavity. The same is not true for trivalent chromium (Cr-III). Thus reduction of Cr-VI to Cr-III in gastric juices is considered a protective mechanism, and it has been suggested that the difference… (More)
DOI: 10.1016/j.taap.2014.08.010

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