A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development.

Abstract

OBJECTIVE N-acetylcysteine (NAC), a cysteine pro-drug and glutathione precursor has been used in therapeutic practices for several decades, as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication. There is a growing interest concerning the beneficial effects of NAC against the early stages of type-2 diabetes… (More)
DOI: 10.1016/j.clinbiochem.2015.04.017

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