A review on the nonoperative removal of necrotic tissue from burn wounds.

@article{Klasen2000ARO,
  title={A review on the nonoperative removal of necrotic tissue from burn wounds.},
  author={H. J. Klasen},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2000},
  volume={26 3},
  pages={207-22}
}
  • H. J. Klasen
  • Published 2000 in
    Burns : journal of the International Society for…
The study of nonoperative debridement of burns got underway during the Second World War. A large number of substances such as enzymes of plant origin, acids and proteolytic enzymes of bacterial origin were examined since. The proteolytic enzymes derived from filtrates of C. histolyticum and B. subtilis have attracted the greatest interest. Although enzymatic debridement would seem at first sight to be an attractive form of treatment, unfortunately the results are highly variable.