A review of three systemic retinoids in dermatology : acitretin , isotretinoin and bexarotene

Retinoids are synthetic and natural analogues of vitamin A that have various effects on cellular differentiation, cellular proliferation, immune system, and embryonic development. The present study reviews the history of systemic retinoids in medicine, the structure of synthetic retinoids and their mechanisms. The main focus is on their biologic functions… CONTINUE READING