A review of the use of adjunctive therapies in severe acute asthma exacerbation in critically ill children

@article{Wong2014ARO,
  title={A review of the use of adjunctive therapies in severe acute asthma exacerbation in critically ill children},
  author={Judith Ju-Ming Wong and Jan Hau Lee and David A. Turner and Kyle J. Rehder},
  journal={Expert Review of Respiratory Medicine},
  year={2014},
  volume={8},
  pages={423 - 441}
}
Asthma is a common and potentially life threatening childhood condition. Asthma involves not only chronic airway remodeling, but may also include frequent exacerbations resulting from bronchospasm, edema, and mucus production. In children with severe exacerbations, standard therapy with β2-agonists, anti-cholinergic agents, oxygen, and systemic steroids may fail to reverse the severe airflow obstruction and necessitate use of adjunctive therapies. These therapies include intravenous or inhaled… 

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