A review of the multiple actions of melatonin on the immune system

@article{CarrilloVico2007ARO,
  title={A review of the multiple actions of melatonin on the immune system},
  author={Antonio Carrillo-Vico and Juan Miguel Guerrero and Patricia Judith Lardone and Russel Joseph Reiter},
  journal={Endocrine},
  year={2007},
  volume={27},
  pages={189-200}
}
This review summarizes the numerous observations published in recent years which have shown that one of the most significant of melatonin’s pleiotropic effects is the regulation of the immune system. The overview summarizes the immune effects of pinealectomy and the association between rhythmic melatonin production and adjustments in the immune system as markers of melatonin’s immunomodulatory actions. The effects of both in vivo and in vitro melatonin administration on non-specific, humoral… 
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