A review of the effects of uranium and depleted uranium exposure on reproduction and fetal development

@article{Arfsten2001ARO,
  title={A review of the effects of uranium and depleted uranium exposure on reproduction and fetal development},
  author={D. Arfsten and K. Still and G. Ritchie},
  journal={Toxicology and Industrial Health},
  year={2001},
  volume={17},
  pages={180 - 191}
}
Depleted uranium (DU) is used in armor-penetrating munitions, military vehicle armor, and aircraft, ship and missile counterweighting/ballasting, as well as in a number of other military and commercial applications. Recent combat applications of DU alloy [i.e., Persian Gulf War (PGW) and Kosovo peacekeeping objective] resulted in human acute exposure to DU dust, vapor or aerosol, as well as chronic exposure from tissue embedding of DU shrapnel fragments. DU alloy is 99.8% 238Uranium, and emits… Expand
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  • 2008
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References

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Abstract : Our laboratory is currently assessing the toxicity of embedded depleted uranium on the female rat This research is intended to answer questions that have arisen following Operation DesertExpand
Biological effects of embedded depleted uranium (DU): summary of armed forces radiobiology research institute research.
TLDR
Results indicate uranium from implanted DU fragments distributed to tissues far-removed from implantation sites, including bone, kidney, muscle, and liver, and suggest the need for further studies of long-term health impact. Expand
Distribution of uranium in rats implanted with depleted uranium pellets.
TLDR
It is concluded that kidney and bone are the primary reservoirs for uranium redistributed from intramuscularly embedded fragments and the accumulations in brain, lymph nodes, and testicles suggest the potential for unanticipated physiological consequences of exposure to uranium through this route. Expand
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This paper assesses the radiological and chemical hazards resulting from the use of depleted uranium (DU) munitions. Due to the low radioactivity of DU, radiological hazards to individuals wouldExpand
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TLDR
An outline of the metabolic pathways of uranium isotopes and compounds, medical consequences of uranium poisoning, and an evaluation of the therapeutic alternatives in uranium internal contamination is presented. Expand
Medical Effects of Internal Contamination with Uranium
The purpose of this work is to present an outline of the metabolic pathways of uranium isotopes and compounds, medical consequences of uranium poisoning, and an evaluation of the therapeuticExpand
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  • E. Hamilton
  • Medicine, Chemistry
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  • 2001
TLDR
Fundamental geological processes are described which illustrate that, as a consequence of routine operation of nuclear reprocessing plants, especially in the past, and following reactor accidents, natural processes can result in an enrichment of DU particles in most types of sediment. Expand
Health effects of depleted uranium on exposed Gulf War veterans.
TLDR
DU-exposed Gulf War veterans with retained metal shrapnel fragments are excreting elevated levels of urinary uranium 7 years after first exposure, suggesting on-going mobilization from a storage depot which results in a chronic systemic exposure. Expand
Surveillance of Depleted Uranium Exposed Gulf War Veterans: Health Effects Observed in an Enlarged “Friendly Fire” Cohort
TLDR
Observed health effects were related to subtle but biologically plausible perturbations in central nervous system function and a general measure of mutagen exposure, related to uranium’s chemical rather than radiologic toxicity. Expand
Urinary and serum mutagenicity studies with rats implanted with depleted uranium or tantalum pellets.
TLDR
It is suggested that uranium content in the urine is correlated with urine mutagenicity and that urinary Mutagenicity might be used as a biomarker to detect exposure to internalized uranium. Expand
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