A review of the current use of rituximab in autoimmune diseases.

  title={A review of the current use of rituximab in autoimmune diseases.},
  author={Hakan M G{\"u}rcan and Derin B. Keskin and Joel N. H. Stern and Matthew A Nitzberg and Haris Shekhani and Abdul Razzaque Ahmed},
  journal={International immunopharmacology},
  volume={9 1},
Rituximab is a human/murine chimeric monoclonal antibody primarily used for treating non-Hodgkin's B-cell lymphoma. Recently it has also been used in the treatment of several autoimmune diseases. A literature review was conducted to determine the efficacy of rituximab in the treatment of some of these autoimmune diseases. Multiple mechanisms proposed for the rituximab mediated B cell depletion are also discussed. The efficacy of rituximab is well-established and it is FDA approved for treatment… CONTINUE READING


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