A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress.

  title={A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress.},
  author={D. Del Rio and A. Stewart and N. Pellegrini},
  journal={Nutrition, metabolism, and cardiovascular diseases : NMCD},
  volume={15 4},
  • D. Del Rio, A. Stewart, N. Pellegrini
  • Published 2005
  • Chemistry, Medicine
  • Nutrition, metabolism, and cardiovascular diseases : NMCD
  • AIM Of the many biological targets of oxidative stress, lipids are the most involved class of biomolecules. Lipid oxidation gives rise to a number of secondary products. Malondialdehyde (MDA) is the principal and most studied product of polyunsaturated fatty acid peroxidation. This aldehyde is a highly toxic molecule and should be considered as more than just a marker of lipid peroxidation. Its interaction with DNA and proteins has often been referred to as potentially mutagenic and atherogenic… CONTINUE READING
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