A review of olanzapine-associated toxicity and fatality in overdose.

  title={A review of olanzapine-associated toxicity and fatality in overdose.},
  author={Pierre S Chue and Peter S Singer},
  journal={Journal of psychiatry & neuroscience : JPN},
  volume={28 4},
OBJECTIVE Given the increasing use of atypical antipsychotics in psychiatric populations and the very limited data concerning the safety of such drugs, we examined the available data on olanzapine in untreated overdose situations. METHODS Available toxicity data concerning olanzapine were obtained from the Offices of the Medical Examiners of Canada, the Canadian Adverse Drug Reaction Monitoring Program and a review of the literature. RESULTS Despite the complexities and limitations of… CONTINUE READING
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