A review of hydrogel use in fracture healing and bone regeneration.

  title={A review of hydrogel use in fracture healing and bone regeneration.},
  author={David Mark Gibbs and Cameron R. M. Black and Jonathan I Dawson and Richard O C Oreffo},
  journal={Journal of tissue engineering and regenerative medicine},
  volume={10 3},
This review explores the application of hydrogels in orthopaedic clinical situations which may benefit from enhanced growth factor delivery and improved osteogenesis of bone graft material. Hydrogels are defined, and in vivo evidence supporting their application in these clinical areas is explored. Our focus is on clinically pertinent properties, such as the chemistry of formation, biocompatibility, efficacy of cell and growth factor delivery, ability to withstand mechanical loading and… CONTINUE READING
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