A review of genome mutation and Alzheimer's disease.

@article{Thomas2007ARO,
  title={A review of genome mutation and Alzheimer's disease.},
  author={Philip W M Thomas and Michael Fenech},
  journal={Mutagenesis},
  year={2007},
  volume={22 1},
  pages={15-33}
}
Alzheimer's disease (AD) is a complex progressive neurodegenerative disorder of the brain and is the commonest form of dementia. The prevalence of this disease is predicted to increase 3-fold over the next 30 years and to date no reliable and conclusive diagnostic test exists that will identify individuals presymptomatically of susceptibility risk. This review examines the molecular, genetic, dietary and environmental evidence underlying the known pathology of AD and proposes a biologically… CONTINUE READING

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