A review of current knowledge of resistance aspects for the next-generation succinate dehydrogenase inhibitor fungicides.

@article{Sierotzki2013ARO,
  title={A review of current knowledge of resistance aspects for the next-generation succinate dehydrogenase inhibitor fungicides.},
  author={Helge Sierotzki and Gabriel Scalliet},
  journal={Phytopathology},
  year={2013},
  volume={103 9},
  pages={880-7}
}
The new broad-spectrum fungicides from the succinate dehydrogenase inhibitor (SDHI) class have been quickly adopted by the market, which may lead to a high selection pressure on various pathogens. Cases of resistance have been observed in 14 fungal pathogens to date and are caused by different mutations in genes encoding the molecular target of SDHIs, which is the mitochondrial succinate dehydrogenase (SDH) enzyme. All of the 17 marketed SDHI fungicides bind to the same ubiquinone binding site… CONTINUE READING