A review of clozapine safety.

@article{Fitzsimons2005ARO,
  title={A review of clozapine safety.},
  author={J. Michael Fitzsimons and Michael Berk and Timothy Lambert and Michel S Bourin and Seetal Dodd},
  journal={Expert opinion on drug safety},
  year={2005},
  volume={4 4},
  pages={731-44}
}
Clozapine is a distinctive antipsychotic agent, having a unique clinical profile and an idiosyncratic safety profile. More so than with other agents, the weighting of its adverse event profile is critical, in order to counterbalance its clear clinical advantages. The safety issues with clozapine are in a number of areas, some of which are considered medical emergencies and potentially life-threatening. These include haematological (neutropenia and agranulocytosis), CNS (seizures… CONTINUE READING
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