A review of central 5-HT receptors and their function

@article{Barnes1999ARO,
  title={A review of central 5-HT receptors and their function},
  author={Nicholas M Barnes and Trevor Sharp},
  journal={Neuropharmacology},
  year={1999},
  volume={38},
  pages={1083-1152}
}
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References

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Silent 5-HT A receptor antagonists: utility as research tools and therapeutic agents
TLDR
The term "silent antagonist' has been introduced to distinguish true 5-HT1A receptor antagonists from partial agonists.
Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents.
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).
TLDR
It is evident that in the last decade or so, a vast amount of new information has become available concerning the various 5-HT receptor types and their characteristics, and it is important to rationalise in concert all of the available data from studies involving both operational approaches of the classical pharmacological type and those from molecular and cellular biology.
The 5‐HT1B Receptors
TLDR
The development of selective 5-HT1B receptor agonists and antagonists will be a key step in defining the physiological role of this receptor site in the brain and periphery of the mouse and rat although it must be realized that these compounds, if they are developed, are unlikely to have functional effects in man since the 5- HT1B recognition site is absent in the human CNS.
[5-Hydroxytryptamine receptors].
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    Nihon yakurigaku zasshi. Folia pharmacologica Japonica
  • 1989
TLDR
Based on a number of pharmacological studies, it seems likely that the mode of action of certain psychotropic drugs is closely related to the activity of central 5-HT receptors.
The structure and signalling properties of 5-HT receptors: an endless diversity?
Novel discriminatory ligands for 5-HT2B receptors
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    Behavioural Brain Research
  • 1995
Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine
The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family.
TLDR
The results demonstrate that the 5HT1D receptors constitute a heterogeneous family of receptors with distinct intracellular signalling properties and expression patterns, and are a distant relative of all previously identified 5‐HT receptors.
5-HT2 receptor subtypes: a family re-united?
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