A review of albumin binding in CKD.

  title={A review of albumin binding in CKD.},
  author={Bj{\"o}rn Meijers and Bert R M Bammens and Kristin Verbeke and P Evenepoel},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={51 5},
Hypoalbuminemia is associated with excess mortality in patients with kidney disease. Albumin is an important oxidant scavenger and an abundant carrier protein for numerous endogenous and exogenous compounds. Several specific binding sites for anionic, neutral, and cationic ligands were described. Overall, the extent of binding depends on the ligand and albumin concentration, albumin-binding affinity, and presence of competing ligands. Chronic kidney disease affects all these determinants. This… CONTINUE READING
24 Citations
102 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 24 extracted citations


Publications referenced by this paper.
Showing 1-10 of 102 references

Major oagulation disturbances during fractionated plasma separa - ion and adsorption

  • Meijers BKI, P Verhamme, F Nevens
  • Am J Transplant
  • 2007

Determi - ation of drug plasma protein binding by solid phase micro - xtraction

  • FM Musteata, J Pawliszyn, MG Qian
  • J Pharm Sci
  • 2006

Superior ialytic clearance of  2 - microglobulin and p - cresol by high - ux hemodialysis as compared to peritoneal dialysis

  • B Bammens, K Verbeke
  • 2006

Therapeutic rug monitoring of mycophenolate mofetil in transplanta

  • TV Gelder, Y LeMeur, LM Shaw
  • Ther Drug Monit
  • 2006

Similar Papers

Loading similar papers…