A review of EPAP nasal device therapy for obstructive sleep apnea syndrome

  title={A review of EPAP nasal device therapy for obstructive sleep apnea syndrome},
  author={Hao Wu and Xiandao Yuan and Xiao-jun Zhan and Li Li and Yongxiang Wei},
  journal={Sleep and Breathing},
BackgroundExpiratory positive airway pressure (EPAP) nasal devices provide a new therapeutic option for obstructive sleep apnea (OSA).MethodsHere, we review the literature about treatment of OSA with EPAP, which has been shown to reduce the apnea/hypopnea index (AHI) and daytime sleepiness.ResultsPatients generally prefer EPAP to continuous positive airway pressure (CPAP), and there are no serious adverse effects from its use. Although CPAP more effectively improves sleep apnea, a recent study… 

Obstructive Sleep Apnea Treatment With Epap Nasal Devices: Physiological Principles and Limitations

The physiological limitations ofEPAP devices during inspiration and during expiration are discussed and the use of EPAP devices with adjustable resistance is essential for best results in treatment of obstructive sleep apnea and snoring.

Efficacy of expiratory positive airway pressure nasal device

Rossi’s conclusion that Provent cannot be recommended as an alternative short-term therapy for patients with moderate to severe OSA already on CPAP does not conflict with the view, based on the many other studies in the literature that were reviewed, that EPAP has shown effectiveness in patients who do not tolerate CPAP.

Efficacy of EPAP

This study looked at the ability of Provention, versus placebo Provent, to protect against the return of OSA following withdrawal of continuous positive airway pressure (CPAP) therapy in a group of patients with a mean ODI of approximately 30 upon CPAP withdrawal.

Gender differences in severity of desaturation events following hypopnea and obstructive apnea events in adults during sleep

While public awareness of sleep related disorders is growing, sleep apnea syndrome (SAS) remains a public health and economic challenge and significant opportunities remain to improve the quality, efficiency, and quantity of treatments.

Non-Cpap Conservative Treatment Alternatives for Patients with Obstructive Sleep Apnea/Hypopnea Syndrome

This review is making an attempt critically to revise the advantages and disadvantages of the proposed conservative methods for diagnosis and treatment of obstructive Sleep Apnea.

Sleep apnea: a review of diagnostic sensors, algorithms, and therapies

A current perspective of the classes of tools at hand is provided, along with a sense of their relative strengths and areas for further improvement, and a set of distinctive therapeutic technologies whose use cases span the continuum of disease severity are provided.

Obstructive Sleep Apnea and Hypertension

Sleep disordered breathing (SDB) is a common disorder characterized by complete or partial obstruction of the upper airway during sleep and apnea caused by decreased central drive of breathing, which

EPAP Devices Optipillows, Bongo Rx, and Theravent: Flow Resistance and The Pressures They Generate

The study shows that the resistances of Theravent and Bongo Rx and Optipillows were identical regardless of how they were calculated, and the three expiratory resistance devices had comparable resistance and generate comparable expiratories pressure.



A novel nasal expiratory positive airway pressure (EPAP) device for the treatment of obstructive sleep apnea: a randomized controlled trial.

The nasal EPAP device significantly reduced the AHI and improved subjective daytime sleepiness compared to the sham treatment in patients with mild to severe OSA with excellent adherence.

Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA).

  • M. KrygerR. BerryC. Massie
  • Medicine
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
  • 2011
Nal EPAP significantly reduced the AHI, improved subjective daytime sleepiness and reduced snoring after 12 months of treatment, and long-term adherence to EPAP was excellent in those who had a positive clinical response at month 3 of the EPAP vs sham study.

Pilot study of nasal expiratory positive airway pressure devices for the treatment of childhood obstructive sleep apnea syndrome.

  • S. KureshiP. Gallagher C. Marcus
  • Medicine
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
  • 2014
NEPAP devices are a potential alternative therapy for OSAS in a small subset of children and should be evaluated with polysomnography, due to variability in individual responses.

Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea.

Although both CPAP and mandibular advancement splint effectively treated sleep-disordered breathing and sleepiness, the expected response in neurobehavioral function was incomplete and may be due to the splint having a lesser therapeutic effect and CPAP being poorly tolerated and therefore used less in this patient group.

A multicenter, prospective study of a novel nasal EPAP device in the treatment of obstructive sleep apnea: efficacy and 30-day adherence.

Treatment with this novel device placed in the nares that imposes an expiratory resistance for the treatment of obstructive sleep apnea was well tolerated and accepted by the participants and an overall reduction in AHI was documented.

Predictors of response to a nasal expiratory resistor device and its potential mechanisms of action for treatment of obstructive sleep apnea.

The present study shows that the nasal valve device can alter SDB across the full spectrum of SDB severity, and suggests that subjects with positional or milder SDB in the lateral position were those most likely to respond.

Compliance to continuous positive airway pressure therapy in a group of Portuguese patients with obstructive sleep apnea syndrome

This study diagnosed a low compliance to CPAP therapy in patients with OSAHS, warning to the need of developing further studies in this area and to theneed of implementing strategies to increase CPAP compliance.

Oral Appliance Therapy versus Nasal Continuous Positive Airway Pressure in Obstructive Sleep Apnea: A Randomized, Placebo-Controlled Trial

There is no clinically relevant difference between MAD and nCPAP in the treatment of mild/moderate OSA when both treatment modalities are titrated objectively.

A pilot evaluation of a nasal expiratory resistance device for the treatment of obstructive sleep apnea.

  • I. ColrainS. BrooksJ. Black
  • Medicine
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
  • 2008
The results of this pilot study are suggestive of a therapeutic effect of expiratory nasal resistance for some OSA patients and indicate that this technique is worthy of further clinical study.