A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD.

@article{Rommelse2008ARA,
  title={A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD.},
  author={Nanda N. J. Rommelse and Marieke E. Altink and Alejandro Arias-Vasquez and Cathelijne J. M. Buschgens and Ellen A. Fliers and Stephen V Faraone and Jan K. Buitelaar and Joseph A. Sergeant and Barbara Franke and Jaap Oosterlaan},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2008},
  volume={147B 8},
  pages={1536-46}
}
Meta-analyses indicate that the gene coding for the dopamine transporter (DAT1 or SLC6A3) is associated with an increased risk for ADHD. The mechanisms of this gene for ADHD are unclear. We systematically reviewed studies linking the VNTR in the 3' UTR of the DAT1 to neurophysiological and neuropsychological measures. In addition, a broad set of executive/cognitive and motor tests was administered to 350 children (5-11 years) and adolescents (11-19 years) with ADHD and 195 non-affected siblings… CONTINUE READING
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