A reversible preparation for observing the behavior of fetal rats in utero: spinal anesthesia with lidocaine.

@article{Smotherman1986ARP,
  title={A reversible preparation for observing the behavior of fetal rats in utero: spinal anesthesia with lidocaine.},
  author={William P Smotherman and Scott R Robinson and B Joan Miller},
  journal={Physiology & behavior},
  year={1986},
  volume={37 1},
  pages={57-60}
}
A technique is described whereby lidocaine with epinephrine is injected into the spinal cord of the pregnant rat to produce reversible spinal anesthesia. This technique is useful for preparing pregnant females to study the spontaneous behavior of their fetuses in utero. Comparison of this procedure with an alternative, but irreversible, spinal preparation (chemomyelotomy) indicates that reversible lidocaine anesthesia does not differentially influence the activity of rat fetuses on Day 19 of… CONTINUE READING