A reverse translational approach to quantify approach-avoidance conflict in humans.

@article{Aupperle2011ART,
  title={A reverse translational approach to quantify approach-avoidance conflict in humans.},
  author={Robin L. Aupperle and Sarah Sullivan and Andrew James Melrose and Martin P. Paulus and Murray B. Stein},
  journal={Behavioural brain research},
  year={2011},
  volume={225 2},
  pages={455-63}
}
Animal approach-avoidance conflict paradigms have been used extensively to characterize effects of anxiolytic agents and probe neural circuitry related to anxiety. However, there are few behavioral approaches to measure conflict in human populations, limiting the translation of findings from animal conflict tasks to human clinical research. We developed a novel approach-avoidance conflict (AAC) paradigm involving situations in which the same decision is associated with "reward" (points) and… CONTINUE READING