A reversal learning task detects cognitive deficits in a Dachshund model of late-infantile neuronal ceroid lipofuscinosis.

@article{Sanders2011ARL,
  title={A reversal learning task detects cognitive deficits in a Dachshund model of late-infantile neuronal ceroid lipofuscinosis.},
  author={Douglas Sanders and Shinichi Kanazono and Fred Alan Wininger and Rebecca E. H. Whiting and Caroline Flournoy and Joan R Coates and Leilani J. Castaner and D P O'brien and Mark L Katz},
  journal={Genes, brain, and behavior},
  year={2011},
  volume={10 7},
  pages={798-804}
}
The neuronal ceroid lipofuscinoses (NCLs) are autosomal recessive lysosomal storage diseases characterized by progressive neurodegeneration and by accumulation of autofluorescent storage material in the central nervous system and other tissues. One of the most prominent clinical signs of NCL is progressive decline in cognitive function. We previously… CONTINUE READING