A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.

@article{Vasios1989ARA,
  title={A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.},
  author={George Vasios and Joseph D. Gold and M. Petkovich and Pierre Chambon and Lorraine J Gudas},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 23},
  pages={9099-103}
}
The retinoic acid (RA)-associated differentiation of murine F9 teratocarcinoma stem cells results in dramatic changes in gene expression. The cellular gene encoding the B1 subunit of the extracellular matrix protein laminin is transcriptionally activated by RA, and its transcription is further enhanced by N6,O2'-dibutyryladenosine 3',5'-cyclic monophosphate (Bt2cAMP) during the differentiation of F9 stem cells into extraembryonic parietal endoderm cells. We now report that expression vectors… CONTINUE READING

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