A retinoblastoma-binding protein related to a negative regulator of Ras in yeast

Abstract

THE growth suppression function of the retinoblastoma protein (Rb) is thought to be mediated by Rb binding to cellular proteins1. p48 is one of the major proteins that binds to a putative functional domain at the carboxy terminus of the Rb protein2. Here we report the isolation of a full-length complementary DNA (RbAp48) encoding p48. Complex formation… (More)
DOI: 10.1038/364648a0

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